Melatonin. Mitochondria. Mitophagy. Autophagy. Oh my! Back pain links them all interestingly.
Melatonin – a hormone secreted by the brain at
night to regulate circadian rhythm – helps sleep which
is vital to the body’s capability to recover
from the day and prepare for the next. Mitophagy promotes healthy
turnover of mitochondria (the energy producers in cells). Mitophagy blocks
the build-up of dysfunctional mitochondria in cells that may precede cell deterioration. In the case of back pain,
this would prevent such disc
cell deterioration which could lead to disc
degeneration. Autophagy is the normal bodily practice
that deals with cell destruction and creation in the
body. When there is cellular stress, autophagy is amplified.
(1) Family & Sports Chiropractic of St. Francisville presents findings that melatonin
and light therapy may intervene in this process and promote
St. Francisville back pain relief.
MITOCHONDRIA AND DISC DEGENERATION
Family & Sports Chiropractic of St. Francisville knows how disc degeneration involves cellular oxidative stress, mitochondria issues and cell death (aka
apoptosis). This is the area researchers suggest
melatonin may play a positive role in the reduction
of disc degeneration. Melatonin gets rid of oxygen free radicals,
adjusts mitochondria function and balance, hastens mitrophagy and reduces apoptosis (cell death).
Melatonin may help treat disc degeneration. (2)
MELATONIN AND LIGHT FOR DISC DEGENERATION AND St. Francisville BACK PAIN
In a biological study of melatonin’s effect on intervertebral
disc degeneration, melatonin maintained nucleus
pulposus cells affected by oxidative stress. Such stress leads
to impairment of these cells. Melatonin is an important
neuroendocrine hormone with sound antioxidant effect that functions
on biological clock regulation. (3) Chronic non-specific low back pain
sufferers who included melatonin in their treatment
plan found it to positively increase the
effect of standard treatments on pain, sleep and depression. The reduced
pain intensity when moving and resting signified that melatonin
potentially has an analgesic
effect. (4) Melatonin may be another treatment of intervertebral disc degeneration.
LIGHT THERAPY AND BACK PAIN RELIEF
Since melatonin is activated
by light and its lack, light treatment assists patients deal
with chronic low back pain, its pain intensity, behavior, and
threshold. It also assists
with post-traumatic stress disorders symptomatology and quality of sleep. All
these were improved with morning bright light treatment of US
veterans with chronic low back pain. (5) Such treatment could certainly
help St. Francisville back pain sufferers, too! These researchers believe
that this light treatment regulates the circadian timing of sleep which
is mediated by melatonin. (5)
CONTACT Family & Sports Chiropractic of St. Francisville
Listen to the PODCAST
with Dr. Chris DeVeau on the Back Doctors Podcast with Dr. Michael
Johnson. A patient struggling with neck pain and arm pain found
difficulty with sleep and relief with Cox® Technic.
Schedule a St. Francisville chiropractic appointment for
your St. Francisville back pain. Patients in St. Francisville with disc degeneration may discover
additional relief with melatonin and light therapy together with chiropractic treatment. Mitochondria, mitophagy, autophagy,
melatonin and back pain are interestingly linked, aren’t they?